Epigenetic Regulation of Neuregulin-1 Tunes White Adipose Stem Cell Differentiation
نویسندگان
چکیده
منابع مشابه
Epigenetic regulation of glioma stem-like cell differentiation
CAPSULE Background: Molecular mechanisms underlying heterogeneity of glioblastoma are poorly understood. Result: Newly identified microRNA-1275, which is controlled by a polycomb-mediated silencing mechanism, regulates expression of oligodendroglial lineage gene, CLDN11, in glioma stem-like cells. Conclusion: MicroRNA-1275 may contribute to the establishment of tissue heterogeneity via epigenet...
متن کاملThe Effect of Human Platelet-Rich Plasma on Adipose-Derived Stem Cell Proliferation and Osteogenic Differentiation
Background: The cultured mesenchymal stem cells (MSC) have been used in many clinical trials however, there are still some concerns about the cultural conditions. One concern is related to the use of FBS as a widely used xenogeneic supplement in the culture system. Human platelet-rich plasma (hPRP) is a candidate replacement for FBS. In this study, the effect of hPRP on MSC proliferation and os...
متن کاملepigenetic regulation of osteogenic and chondrogenic differentiation of mesenchymal stem cells in culture
management of mesenchymal stem cells (mscs) capabilities to differentiate into osteogenic and chondrogenic lineages would be of utmost importance for their future use in difficult to treat cases of destroyed bone and cartilage. thus, an understanding of the epigenetic mechanisms as important modulators of stem cell differentiation might be useful. epigenetic mechanism refers to a process that r...
متن کاملEpigenetic regulation of stem cell fate.
Stem cell-based regenerative medicine holds great promise for repair of diseased tissue. Modern directions in the field of epigenetic research aimed to decipher the epigenetic signals that give stem cells their unique ability to self-renew and differentiate into different cell types. However, this research is only the tip of the iceberg when it comes to writing an 'epigenetic instruction manual...
متن کاملDifferentiation of Adipose-derived Stem Cells into Schwann Cell Phenotype in Comparison with Bone Marrow Stem Cells
Objective(s) Bone marrow is the traditional source of human multipotent mesenchymal stem cells (MSCs), but adipose tissue appears to be an alternative and more readily available source. In this study, rat adipose-derived stem cells (ADSCs) were induced to differentiate into Schwann-like cells and compared with rat bone marrow stem cells (BMSCs) for their Schwann-like cells differentiation pote...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: SSRN Electronic Journal
سال: 2020
ISSN: 1556-5068
DOI: 10.2139/ssrn.3517531